Metolachlor

CAS Number: 51218-45-2

English name: Metolachlor

Chemical Name: 2 - chloro -2 ', 6'-diethyl-N-(2 - propoxy) ethyl acetyl for aniline; 2-Chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl) acet amide

Other name: DU ear; Dole; toxic grasses; rice Enthone

Molecular formula: C15H22ClNO2

MW: 283.79

Properties: pure product is colorless liquid, industrial products, brown oily liquid.bp100 ℃ / 0.133Pa, vapor pressure of 1.73 × 10-3Pa (20 ℃), the relative density of 1.12 (20). Soluble in methanol, ethylene dichloride and other organic solvents, in the water solubility of 530mg / L. Photolysis is not easy, storage stable for two years, half-life of 25d. 

Toxicity: Acute oral LD50 is 2780mg/kg, acute dermal LD50> 3170mg/kg, acute inhalation LC50> 1750mg/m3 (4h). No stimulating effect on rabbit eyes, mild irritation to the skin. No effect 90d feeding experiment in rats a dose of 1000mg/kg, dog 500mg/kg. 2-year feeding experiment in rats had no effect dose of 1000mg/kg, mice 3000mg/kg. No animal testing teratogenic, carcinogenic, mutagenic effect. Toxic to fish, rainbow trout LC50 is 3.9mg / L, catfish LC50 is 4.9mg / L. Low toxicity for birds.Toxic to bees have the stomach, but no contact toxicity. 

Role of the characteristics and uses: product is 2 - acetyl chloride for the aniline herbicides, is cell division inhibitors, selective herbicide before seedlings. Weeds through the shoots, young roots absorb the agent, the inhibition of protein synthesis to death. For corn, soybean, canola, cotton, sorghum, vegetables and other crops, prevention crabgrass, barnyard grass, Eleusine indica, Setaria, daughter son, teff and other annual grass weeds, broad-leaved grass control effect on the poor broad-leaved weeds such as grass mixed with students, both agents can be mixed before use. Control in soybean, corn weeds after sowing with 72% prior to the emergence of EC, 15 ~ 23mL/100m2 the water spray the soil surface. Usually use 3 ~ 5d before planting. Single application of the product when wet transplanting rice less selective when used in conjunction with the pyridine solution grass on the line when the rice has an excellent selectivity. If the products and solutions to the grass mixture Triplidine 600 +200 gai / ha used on Monochoria grass, sedge shaped, pointed petals flowers, Fimbristylis and other effects were more than 90%, while for the daughter of 100% sub-control effect . 

Formulation: 72% EC, 

Production methods: first by 2 - methyl -6-- ethyl aniline and 2 - chloro-propanol the reaction of N-(1 - methyl -2-- hydroxyethyl) -2-- methyl -6-- ethyl aniline, chloroacetyl chloride and then reacted with N-(1 - methyl -2-- hydroxyethyl) acetyl chloride for 2 - methyl -6-- ethylaniline. The latter reacted with methanol Pretilachlor. Another production method is to make 2 - ethyl -6-- methyl aniline and 2 - bromo -1-- methoxy-propane at 120 ℃, 1.33kPa under stirring 40h,, 2 - ethyl -6-- methyl - N-(1'-methoxy - C -2--) aniline, and then in the presence of triethylamine, benzene solution of the above intermediate chlorobenzene was added acetyl chloride solution at room temperature stirred 2h, after washing, drying, distillation Pretilachlor products.Consumption of raw materials fixed: 2,6 - diethylaniline 540kg / t, 2 - bromo -1-- methoxy propane 310kg / t, triethylamine 510kg / t, benzene 40kg / t. 

Production Status: Currently there are farmers in Shandong coast, Shandong Overseas Chang, Hangzhou Qingfeng, Jiang Changlong, Henan Gold Fields to agricultural, biological and chemical Bluecrop Jiangsu, Chongqing, Winbond, Zhejiang, Ying Tai, Dalian Ruize, and other 16 non-Xi Ruize Swiss Syngenta enterprises and foreign enterprises registered a production of the original drug, total capacity of 30,000 tons / year. 

Price: Propisochlor original drug price 24000 yuan / ton (10.12)

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