According to the latest research abroad, as long as the taking out of a newly developed "longevity medicine", it can be returned in a short time from 80 years old 50 years old, aging may also be caused by various diseases cured ... ... scientists States trying to find the human body not only in the lives of all clock, but be delayed by the clock trying to find the method. If you have a short sigh of life, let us work together to sweep aside the "longevity medicine" veil of mystery, to explore the mysteries of eternal youth.
Opened modern medical history, we can easily find all the human efforts made so far revolves around improving health and quality of life and prolong human life to this theme. We should clearly realize that: aging and death is the biological law of nature. So, whether it is "youth" of telomerase, anti-oxidation "斯库拉乔夫 ion" or "branched-chain amino acids", "elixir of life" is not the ultimate goal of the study to extend human life indefinitely, but by scientific means to extend the life cycle of the youth period.
Italy: branched-chain amino acids can prolong life
"The first evidence of human amino acid mixture to prolong the life of 。"--- taught Enzo NESO
Key words: branched-chain amino acids
By the leucine, isoleucine and valine amino acid composition of these three kinds of mixtures.
Italian scientists have successfully developed a drug to prolong life, and has conducted experiments on mice in the small, the effect is significant.
This wonderful drug from leucine, isoleucine and valine amino acid composition of this mixture of 3, the scientific name "branched-chain amino acids." During the experiment, the researchers gave mice drinking water was tested by adding these 3 amino acids and found that their average life span was 869 days, while normal mice can only survive about 774 days. In other words, "branched-chain amino acids," the mice's life span by 12%.
While the extension of life, the body also occurs in mice a series of positive biological responses, such as cells can be more energy intake, and reduction of free radicals. Free radicals are produced in the body of harmful oxidation of compounds with strong oxidizing, can damage the body's tissues and cells, thereby causing chronic diseases and aging effects. After these changes in vivo, mice appear vibrant, and improved muscle coordination.
"Human first proves, amino acid mixture can extend the life of mice." Principal investigator of the study, from the University of Milan, said Professor Enzo NESO in. He also pointed out that if this amino acid supplements on the basis of the invention, it is likely to benefit mankind in the future, for the great help the elderly or patients, especially those with lower levels of cells characterized by the diseases, such as heart failure or chronic lung disease patients.
Of course, testing the feasibility of the human body remains to be seen. The current test is done on animals, and animal response to drugs and human response varies enormously effective drug in animals, in humans, may be invalid. In addition, individual differences also need to consider.
United States: changes in telomere length in the first successful reverse aging test
"By 2025, the world will have 1.2 billion over the age of 60 years old, this age are beginning to susceptibility to cancer, Alzheimer's disease and cardiovascular disease. We are about to face a heavy social burden. This trial is the first successful reverse the aging process. "- Ronald Durbin Huo
Key words: telomere
Telomeres are the ends of chromosomes covering DNA repeats to help cells resist aging, prevent chromosome damage, has often been likened to "both ends of shoelaces to prevent wear of the plastic sleeve."
Little decided to aging telomere
Remember the Hollywood blockbuster "youth" in the plot of it? Brad Pitt played the main role of Benjamin Button singular violation of the law of nature, have to resort to old image of the birth of the world, after living longer and younger. Now the story of the film is staged reality. Recently, Harvard University Hall oncologists under the telomere theory of Ronald Durbin, through the rat study, the first successful reversal of the aging process, the research published in "Nature" magazine.
This not only makes a more longevity elixir, from Alzheimer's disease and heart trouble, has beautiful skin and shiny hair, as well as possible for women in natural fertility age children.
Test, De Binhuo special method by premature aging in mice, so that the skin of these animals, brain, viscera and other organs like the elderly and 80 years of age; and then use drugs to stimulate the success that telomerase reverse transcriptase back to life. Mice 2 months after medication, a large number of new cells grow, rejuvenate, revitalize. More surprising is amazing that the original old male mice restored fertility, re-breed.
Where the magic hiding telomere
Biologists have long known that an interesting fact: that the life of each cell has a certain limit, in artificial culture conditions, close to the limit, even with the best training methods can not save the established fate. Like human fibroblasts, according to tests, can only breed 50 generations will tend to die. Like other mouse fibroblasts can split the 18 generations, the turtle fibroblast cell division 110 generations. Found that the number of clock control of cell division is the telomere.
The so-called telomeres, is covering the ends of chromosomes DNA repeats. Telomeres prevent chromosome damage, and is often likened to "both ends of shoelaces to prevent wear of the plastic sleeve." In the new cells, each cell division time, telomeres shorten it a bit, over time, the telomeres get shorter, which increases the risk of age-related diseases such as Alzheimer's risk. Until they become too short, the cells die.
In 1984, scientists in molecular biology research on single-cell organisms, they found an enzyme that maintains telomere length - Telomerase, and reveals its peculiar role in the human body: In addition to human germ cells and some cells In addition, almost all other cells of telomerase does not work, but it can maintain telomere length of cancer cells, to unlimited expansion. Telomere telomerase reverse transcriptase can recycling, but the body will tend to turn off this enzyme. Many biologists telomerase called "immortality enzyme", so that life springs eternal, because it has the power at the cellular level, "so that life will last."
"Youth" take some time before
De Binhuo that eventually should be able to develop a can produce the same effects in humans of drugs, but so far, the study also faces tough challenges: Telomerase appears in almost all cancer cells, which means that telomerase may lead to unrestricted cell proliferation. The De Binhuo the successful development of the high level of telomerase reverse transcriptase will accelerate tumor growth.
De Binhuo said: "aging is caused by a variety of common mechanisms. Thus, while we believe that telomeres are important, but there are other factors also play an important role." Telomere expert at Harvard University, Steven Asia Dr. Tandy said the study "very nice", but he also warned that an anti-aging drugs can only be reversed up to 10 years time.
Russia: anti-oxidation ion "longevity medicine" is expected to come out after two years
"We hope to eventually make people believe that a pill will be able to repel the threat posed by aging." - 斯库拉乔夫 son
Key words: "斯库拉乔夫 ions"
This is a powerful antioxidant, can prevent oxygen in-depth within the cell, it can exercise in a particular range of small, medium, and cells in a dangerous form of oxygen, eliminate the negative effects of oxidation on the human body, thus prolonging life.
Department of antioxidant principles of longevity medicine
Russian scientist Vladimir 斯库拉乔夫 said he developed an anti-aging drugs can be expected to enter the market within two years.斯库拉乔夫 aged 69, worked at Moscow University, engaged in more than forty years of anti-aging drugs.
Energy exchange process in human cells need oxygen, but it will still be oxygen damage. Although scientists have found that some natural antioxidants, but their effect is not lasting.
"In 99% of the cases, the oxygen will become harmless water," British media quoted 斯库拉乔夫 saying, "but there will be 1% of the oxygen superoxide, followed by a strong toxic substances. Therefore, my task is to find an anti-oxides, to stop this process. "
斯库拉乔夫 to this new type of anti-oxidants, nicknamed "斯库拉乔夫 ion." This is a powerful antioxidant, can prevent oxygen in-depth within the cell, it can exercise in a particular range of small, medium, and cells in a dangerous form of oxygen.
Double life of animal testing
斯库拉乔夫 said, based on the "斯库拉乔夫 ion" create a new drug to eliminate the negative effects of oxidation on the human body, it is to avoid the risk of elderly patients, thus prolonging the life of many decades.
In 2004, 斯库拉乔夫 to something called the "eternal elixir" of the material implanted rat, the results show that doubling the life of mice, but become more healthy. In addition, the production of anti-oxidants with eye drops that make some elderly patients because of blinding horses, dogs and rabbits to restore vision.斯库拉乔夫 also themselves as "white mouse", cured of cataract in one eye.
Geoff of Kula, said the research results of clinical trials needed for two years. Currently, clinical trials have already started, thousands of people signed up. And several years ago, 斯库拉乔夫 and a geneticist at the University of Cambridge Professor Gray had suggested that life expectancy can be up to 800 to 1000 years old, or even longer.
Even behind the question is still under
斯库拉乔夫 research Chengguo, backed by many celebrities, including Nobel Laureates Beijing 特布洛贝尔, he said: "The experiments show that the oxidation caused great damage to the human body. Basescu Lajoie Fu Boshi is the world's best scientists in Biochemistry and Bio Energy. "
However, in theory, relative to the telomere theory, antioxidants alone the possibility to achieve longevity seems to be more slim, voices of doubt are many:
First of all, the human body is like a huge "biochemical factory", simply an "antioxidant" can not solve all the problems.
Second, the oxide free radicals can lead to various diseases, even to some extent, antioxidants can fight free radicals, but can not stop the process in the development of human exposure to the pathogen may occur, gene mutation, metabolic problems, cancer invasion and so on.
Finally, the body 14 of a total of 10 power cells, which is an astronomical figure, how can these antioxidants were injected into each cell it? Is to allow people to eat, or injection?
No comments:
Post a Comment