WG 80 of the last century developed a new pesticide formulation, because of its safety, free of organic solvents, no dust, packaging, transportation, ease of use have developed rapidly. As a new environmentally friendly pesticide formulations is an important direction of development, water dispersible granule pesticides at home and abroad in recent years has become the main dosage forms. Domestic enterprises in the development of water dispersible granules registration and promotion are highly enthusiastic.
According to the Science and Technology Research Institute of Chemical Engineering professor Zhang Zongjian introduction, water dispersible granule is a rapidly disintegrating into the water dispersed into the solid-liquid dispersion system with high suspended granular formulations, do not use organic solvents, the active ingredient content as high as 50% to 90%, dispersion, suspension stability, suspension rate more than 90%, degree of dispersion of fine particles after 8 to 10 microns, efficacy and product performance. Pesticide active ingredients not easily soluble in water and organic solvents, pesticides melting point higher than 70 ℃ varieties are suitable for processing into water dispersible granules.
Despite rapid development, but because of the domestic new pesticide formulations in the upgrading of more than ten years behind the developed countries, and therefore the understanding of the formulation is still a wide gap compared with developed countries, especially in the formulation of research, production process development, equipment for continuous production, process control, dust control, the production process there is still much to study and explore the subject. At present, many products labeled water dispersible granule Although the name, but the uneven quality of products, processing technology is also quite different. In addition, China's production of pesticides in water dispersible granules smaller overall size, production technology is relatively backward technology and equipment, supporting research and production lagged behind additives, product quality is unstable, practitioners estimate that 30 more companies, but more than 1,000 tons of production capacity not more than five.
According to Anhui Research Institute of Chemical Engineering professor introduced the right to wear, water dispersible granules processing sub-wet process and dry process of two. Granulation process as the formulation of one of the core technology of production, divided into spray granulation, rotary granulation, fluidized bed granulation and extrusion granulation of four. From the analysis of processing advantages, in terms of production, consumption, environmental and product adaptability of view, are regarded as the most competitive extrusion granulation of water dispersible granules production methods, but there is still much to enhance the degree of continuous space.
Zhang Zongjian that the WG should focus on research and development in process selection, promoter selection and safety performance, product performance and efficacy, quality and formula to adjust the original drug and other aspects of the issues in order to speed up the processing of a scientific and rational way.
Among them, the water dispersible granule product processing technology selection should take into account the scale of investment, continuous level and stability of the original source of drug quality and other factors. Zhang Zongjian that the wet granulation and dry granulation advantages and disadvantages, the choice of specific issues should be treated. In the auxiliary selection, water dispersible granules used in wetting agents, dispersing agents more types of key additives, and many are organic polymer material, the choice of product brands and should pay attention to the stability of supply, occurred at the supplier changes must first verify the test reproduction. It is understood that the current domestic water dispersible granule key additives used in many large foreign companies monopolized by the few, and only polymer carboxylate dispersant several special additives to achieve a localization.
Wearing the right to point out that the water dispersible granules processing pharmaceutical processing also followed the direction, because the pesticides of the most advanced processing techniques are often extended over the field of medicine. May, according to the positioning of their products to determine the choice of which way the production process.
Made things up (Nantong) Co., Ltd. General Manager of Hui-Ming Zhang WG pesticide industry turned into a analysis. In his view, water dispersible granule pesticides production needs formula, process, three technical support and equipment, which is the core formula, process is the key equipment is the foundation. Water dispersible granule pesticides currently in the development of a critical moment, to speed up the upgrading of pesticide formulations, and he proposes to strengthen policy guidance to the next 3 to 5 years to gradually replace most of the WP, to guide large-scale processing of the original drug companies and agents companies to establish long-term stability through the product chain of division of labor relations, by doing large-scale industrialized advantage. Furthermore, it should establish and improve standardization system, improve the quality of water dispersible granules; attention to scientific research, form a system complete industrial chain, encourage safety, environmental protection, clean production technology and advanced research, and actively develop special equipment, help support the function Development and application of independent agents.
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