Uniconazole

Uniconazole 

CAS Number: 83657-22-1 

English name: Uniconazole 

Chemical Name: (E) -1 - chlorophenyl -2-- (1, 2, 4 - triazole -1-- yl) -4, 4 - dimethyl -1-- pentene -3-- alcohol; (E )-(+-)- ylethyl); (e) -1 - (4-chlorophenyl) -4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3- ol 

Other names: High yl; effects yl, Sumgaic, Prunit, S-3307, S-327, XE-1019 

Molecular formula: C15H18ClN3O 

Molecular weight: 291.8 

Structure: 

Physical and chemical properties: Appearance light yellow to white solid or even loose powder, melting point 147 ~ 164 ℃, vapor pressure 8.9mPa (20 ℃), relative density 1.28 (21.5 ℃). . Solubility (25 ℃): water 8.41mg / L, methanol 88g/kg, xylene 7g/kg, hexane 300mg/kg, can be dissolved in acetone, ethyl acetate, chloroform, dimethyl sulfoxide. Under normal storage conditions and high stability. 

Toxicity: low toxicity to humans and animals. Oral LD50 in male mice rats 4000mg/kg, female 2850mg/kg. Moderate toxicity to fish, goldfish TLM48h> 1.0mg/kg, blue gill fish 6.4mg/kg, carp 6.36mg/kg. 

Role of the characteristics and uses: uniconazole is a triazole broad-spectrum efficient plant growth regulators, both bactericidal and herbicidal effect is gibberellin synthesis inhibitor. With control vegetative growth, inhibition of cell elongation, shortening Festival, the dwarf plants, and promote lateral bud growth and flower bud formation, improve stress resistance. Activity 6-10 times higher than the MET, but its residues in soil paclobutrazol only 1 / 10, and therefore little influence after the crop, through seeds, roots, buds, leaves, absorption, and in the organs of each other operation, but leaves out running absorbs less. To the top of the obvious. For rice, wheat, increase tiller, controlling plant height, increase lodging resistance. Used to control the vegetative growth of fruit tree. Ornamental plant morphology for control, and promote flower bud differentiation and more flowers and so on. 

Usage: 

1. Paddy rice seeds with 50-200mg/kg. Rice with 50mg/kg, single cropping of rice, or even for different varieties of rice for soaking liquid with 50-200mg/kg, seed volume and liquid ratio was 1:1.2:1.5, soaking 36 (24-28) h, mixing every 12h species 1, in order to facilitate uniform seed the drug. Then after washing with a small amount of primed seed. Stocky seedling tiller can be more nurturing. 

2. Wheat Seed dressing liquid with 10mg/kg, 10mg/kg per kg seeds with liquid 150ml, side spray while stirring, the liquid evenly attached to the seeds, and then mixed with a small amount of fine dry soil mix in order to facilitate sowing. Dressing can also be bored after 3-4h, and then mixed with a small amount of fine dry soil, planting mix. Cultivation of winter wheat seedlings could enhance the resistance, increased tillering years ago to improve the spike rate, reduce the seeding rate. In wheat jointing stage (better early than late), mu evenly spraying liquid uniconazole 30-50mg/kg 50kg, can control the wheat elongation, increased lodging resistance. 

3. Ornamental plants to 10-200mg/kg liquid spray to 0.1-0.2mg/kg basin irrigation liquid, or liquid in the dip before planting to 10-1000mg/kg roots, corms or bulbs a few h, can be controlled individual plant, and promote flower bud and blossom. 

4. Peanuts, grass and so on. Dosage: 40 grams per acre, with 30 kg of water (about two pot) 

Formulation: 5% WP. 

Production methods: 1.α-(1,2,4 - triazol -1-- yl) pinacolone Preparation: 0.2mol pinacolone will dissolve in 80mL glacial acetic acid, dropping 32g bromine reaction drops to 0.5 Bi h, have α-bromo pinacolone, the yield was 67%. Then 13gα-bromo pinacolone dropped into the 5.3g 1,2,4 - triazole and sodium ethoxide (1.9g sodium and 40mL ethanol) mixture, reaction, α-handled by the post (1,2,4 - triazol -1-- yl) pinacolone yield of 76.7%. 

2. "Triazole enone" Preparation: The 0.05molα-chlorobenzaldehyde, 0.05molα-(1,2,4 - triazol -1-- yl) pinacolone, 50mL of benzene, and a certain amount of organic base, the reaction 12h, by post-processing was "triazole ketene", the yield was 70.3%. Another report, in the light, heat or catalyst, so that the "triazole ketones" Isomerization, "triazole ketones" Isomerization of Z configuration can translate into E configuration. 

3. Synthesis of uniconazole: The above product dissolved in 50mL of methanol, sodium borohydride in batches adding 0.33g, reflux 1h, steamed out of methanol, added 1mol / L hydrochloric acid 25mL, produces a white precipitation, filtration, drying, ethanol re- crystallization may uniconazole, the yield was 96%.