zhongshengmycin

Name gram bacteria Kang 

English common name zhongshengmycin 

Formula C19H34O8N8 

Structure 

    

Fungicide pesticide category 

CA Registry Number 

Chemical classification of biological sources 

Chemical Name 1-N glycoside-based chain fixed base -2-- amino-deoxy-L-lysine -2 glycosaminoglycans Ancient Law 

Analysis HLPC Law (Arbitration Act), bioassay 

Zhongshengmycin produced in bacteria is Streptomyces, numbered B-7, is by the Chinese Academy of Medical Sciences, Institute of Medicinal Biotechnology, isolated from Hainan to the soil, biological control by the Chinese Academy of Agricultural Sciences Research and Development Institute to become a variety of biological pesticides. Selected strains from 1986 to 1996 to obtain temporary registration of pesticides. Is a new agricultural antibiotic from Streptomyces lavendulae gray antibiotics produced variants of Hainan. Formulations of the bacteria is a sterilization process wide spectrum of protective fungicides, with contact, penetration effect. Zhongshengmycin active ingredient in a 6, in ascending order between the various components of a β-lysine. It is typical of alkaline water-soluble antibiotic group, the mixture of the UV spectrum shows only end absorption in each group were similar to the infrared spectrum, are all L-compounds. Of Zhongshengmycin are N-glycoside antibiotics, UV absorption spectra for the end of Sweden, the general can not be detected by ultraviolet range, and only by pre-column sample and phosphorus phthalaldehyde (Ophthalaldehyde) derivative under appropriate conditions the reaction of a fluorescent product, and then to reversed-phase ion pair chromatography for separation, detection by fluorescence detector. 

Characters pure white powder, the original drug to light yellow powder, soluble in water, slightly soluble in ethanol. In acidic medium, low temperature stability, melting point 173-190 ℃, 100% soluble in water. Preparations for the brown liquid, PH value of 4. 

This product is low toxic fungicide toxicity, male and female rats acute oral LD50 316mg/kg, male rat acute oral LD50 2376mg/kg. Acute oral LD50 greater than 2000mg/kg 

Formulation: 3% WP, 1% AS and the original drug mixed with other preparations, such as 53% in Fujian Kaili Zhongshengmycin carbendazim WP and mixed formulations with other drugs. 

Mechanism: inhibition of pathogenic bacteria proteins by peptide bond formation, leading to bacterial death; inhibit the mycelium growth of fungi, inhibit spore germination of fungal diseases play a role in prevention and treatment; can stimulate phytoalexin and lignin in plants the formation of the precursor material, thereby enhancing plant disease resistance. 

The role of the object: a broad spectrum antibiotic, resistant Gram-positive and-negative bacteria, mycobacteria, yeast and filamentous fungi, especially pathogens on crops such as cabbage soft rot bacteria, cucumber angular leaf spot bacteria Xanthomonas oryzae, Apple ring rot monocytogenes have obvious antibacterial activity. 

The application of Zhongshengmycin: bacterial blight of rice strains MIC is 0.19μg/ml, MBC is 0.4μg/ml; of Chinese cabbage soft rot bacteria MIC is 1.56μg/ml, MBC is 3.12μg/ml; on Apple Pathogen of the MIC is 1.56μg/ml, MBC is 3.12μg/ml. Field use of low concentration, control the concentration of these three diseases is generally used 30-40μg/ml. He harmful effects in the treatment of bacterial or more prominent, merger is also good protection capability of fungi. Bacterial diseases are on the special effects, while higher fungi cause diseases also have some effects, such as anthrax; but bacterial flagellum Amon disease caused by fungus is not valid, such as the late epidemic, downy mildew and so on. 

The specific use of Zhongshengmycin 

Control objects and methods used during the concentration and method of use 

Apple ring rot, anthracnose, leaf spot and mildew heart disease, bacterial shot hole of peach blossom spray 1st start, after 1 spray every 15-20 days, post-spraying with Bordeaux mixture alternately, the bacteria factors were sprayed 4-5 times. 30-40μg/ml Spray 

Soft rot of Chinese cabbage seed dressing + seedling to rosette stage spray 2 60μg/ml (dressing) 30-40μg/ml spray 

Solanaceae vegetables wilt early stages IRRIGATING consecutive 2-3 times 30-40μg/ml IRRIGATING 

Bacterial angular leaf spot of cucumber, bean bacterial blight, asparagus stem blight, scab incidence of pepper spray since the early spray 30-40μg/ml 

Bacterial blight of rice warm water (55 ℃) +5 natural temperature soaking leaf seedling stage 36-48 hours + 5 days before transplanting the spray once; incidence in the field spray again. 80μg/ml (Soaking)

30-40μg/ml Spray 

Start from the shoots of citrus canker spray once every 10 days, a total of spray 6-8 times. 30-40μg/ml Spray 

Soaking + early stages, ginger root pouring 30-40μg/ml IRRIGATING 

(1) prevention of bacterial diseases of vegetables. Cabbage soft rot, bacterial wilt of Solanaceae times in the early stages, the liquid spray with 1000-1200, a total of 3-4 times; on the ginger blast soaking liquid can be 300-500 times of 2h after seeding, growing by 800 - 1000 times Guangen, 0.25kg per plant liquid, filling a total of 3-4 times; on cucumber bacterial angular leaf spot, common bean bacterial blight, bacterial fruit rot of watermelon in the early stages, the liquid spray with 1000-1200 times . 1 spray every 7-10 days, were sprayed 3-4 times. 

(2) control of rice bacterial leaf blight, Bakanae. 5-7 days of soaking with 600 times, the early onset of 1000-1200 times the liquid and then spray 1-2 times. 

(3) disease prevention and control of fruit trees. Apple ring rot, anthracnose, leaf spot, mildew disease, grape anthracnose, anthracnose of watermelon wilt, anthracnose and other diseases may be the early onset of spray, diluted 1000-1200 times using a total of 3 - 4. Against apple diseases, can start spraying at flowering. 

Note: 

(1) can not be mixed with alkaline pesticides. 

(2) Prevention and early onset of drug effect is remarkable. Spraying should be uniform, and thoughtful. If the rain should be completed after application spray. 

(3) IRRIGATING. 

Of Zhongshengmycin as an agricultural pesticide resistant variety, has made three certificates, registered in the Ministry of Agriculture, rice bacterial leaf blight, apple ring rot, cabbage soft rot, bacterial angular leaf spot of cucumber, bean bacterial disease, asparagus stem blight, scab pepper, ginger, citrus canker, bacterial wilt of tomato and so on.